Faculty of Dentistry

Academic Members

Faculty Member, PhD Siğnem Eyuboğlu

Faculty Member, PhD
Siğnem Eyuboğlu

Fizyoloji

Asst. Prof. Siğnem Eyuboğlu graduated from Haliç University Molecular Biology and Genetics department in 2008 and got her master's degree in physiology from Kardeniz Technical University in 2013. She performed her PhD in experimental brain mapping and electrophysiology at Capa Medical Faculty, Istanbul University. She worked for ten years at Physiology Department Faculty of Medicine,Yeditepe University. Her major research interests are neuroendocrinology, neuroscience and cognitive behavior. She has experiences about optogenetics, chemogenetics and behavioral brain circuits. Dr. Eyuboglu joined the faculty of medicine at Istinye University in 2019.

Araştırma Alanları

  • Kisspeptin Nöronal Devreler ve Nöroanatomik Haritalama
  • Optogenetik ve Farmakogenetik manipülasyonlar
  • Bilişsel ve Davranışsal Sinirbilim
  • Öğrenme ve Hafıza Alzheimer Hastalığı
  • Endokrin Bozucular

Çalışma Alanları

  • Sağlık Bilimleri Temel Alanı
  • Fizyoloji
  • Anti-Apoptotic Effects Of Valproic Acid Treatment On Dopaminergic Neuronal Loss In A 6-Hydroxydopamine Model Of Parkinson\u2019s Disease In Rats, 2022
  • Polychlorinated biphenyls and organochlorine pesticides in breast milk samples and their correlation with dietary and reproductive factors in lactating mothers in Istanbul, 2021
  • Comparison of the Effects of Dovitinib and Bevacizumab on Reducing Neovascularization in an Experimental Rat Corneal Neovascularization Model, 2019
  • Comparison of the neuroprotective effects of brimonidine tartrate and melatonin on retinal ganglion cells, 2018
  • Investigation of the effects of kisspeptin-10 in methionine-induced lipid peroxidation in testicle tissue of young rats, 2017
  • Postacute Effects of Kisspeptin-10 on Neuronal Injury Induced by L-Methionine in Rats, 2014
  • Promoter Methylation in Epithelial-Enriched and Epithelial-Depleted Cell Populations Isolated from Breast Milk, 2014
  • Leptin regulation of pubertal maturation in intact and pinealectomized female rats, 2013
  • Effects of the gonadotropin-releasing hormone antagonist cetrorelix in the early postimplantation period on rat pregnancy, 2011
  • Effects of kisspeptin-45 on neural lipid peroxidation in male rats, 2012
  • Promoter methylation in epithelial cells isolated frem breast milk of women from Istanbul, Turkey, 2013
  • Effect of c-Abl gene silencing by siRNA on proliferation of Mouse granulosa cells, 2015
  • Chronic manuplation of arcuate kisspeptin neurons in AB1-42 induced mouse model of Alzheimer’xxs disease, 2018
  • Investigation of effects of kisspeptin10 in methionine induced lipid peroxidation in testis tissue of young male rats., 2015
  • Investigation of epigenetic changes in exfoliated mammary epithelial cells retrieved from lactating women, 2015
  • Effects of chronic infusion of kisspeptin and its antagonist on cognitive functions and behavior in female rats, 2013
  • Midkine, TNF-a and cytochrome C expressions in kainic acid induced epileptic seizures in rats., 2015
  • Comparison of exfoliated human mammary cells count with demographical and nutrional parameters of lactating mothers, 2014
  • HÜCRESEL TIP VE MEDİKAL BİYOTEKNOLOJİ UYGULAMALARI, ISBN: 978-625-7401-52-4, 2021