Faculty of Dentistry

Academic Members

Remzi Okan AKAR

Remzi Okan Akar,  Research Asst.

CV

R. Okan Akar after graduating from the Molecular Biology and Genetics Department of Istanbul Kültür University, where he graduated with a second degree in 2017, completed his master's degree in Cancer Biology and Pharmacology at Istinye University. He is currently doing his doctorate in the molecular oncology program of Istinye University. He is also co-founder of Ovoboard Biyoteknoloji A.Ş. During his master’s, he worked as an intern at the Karolinska Institute Oncology-Pathology department in Sweden. He has been involved in laboratory studies for more than six years from the undergraduate level. He is working on molecular cancer pathways, anti-cancer drug discovery, and cell death. He is a member of the Molecular Cancer Research Association (MOKAD) and EACR (European Association for Cancer Research). He has published 10 articles in international journals. In addition to being a research assistant at Istinye University Medical Faculty Medical Biochemistry Department, he also works at Istinye University Molecular Cancer Research Center (ISUMKAM). His hobbies include science fiction-fantastic literature and basketball.

Research Areas: Cancer Biology, In ovo, CAM assay, Cell Death, Molecular Biology, Posttranslational Modifications, Protein- Protein Interaction

Main Areas: Moleküler Biyoloji ve Genetik,  Moleküler Biyoloji, 

Synthesis, DNA Binding and Cytotoxic Activity of Newcopper(II) Complexes of Trisubstituted Imidazoles
2022 - Uluslararası Hakemli
Pharmaceutical Chemistry Journal, GERÇEK ZUHAL, YILDIZ UFUK, ULUKAYA ENGİN, AKAR REMZİ OKAN
Highly Promising Antitumor Agent of a Novel Platinum(II) Complex Bearing a Tetradentate Chelating Ligand
2020 - Uluslararası Hakemli
ACS Medicinal Chemistry Letters, YILMAZ İSMAİL, AKAR REMZİ OKAN, Erkisa Merve, Selvi Selin, Sengul Abdurrahman, ULUKAYA ENGİN
A promising therapeutic combination for metastatic prostate cancer: Chloroquine as autophagy inhibitor and palladium(II) barbiturate complex
2020 - Uluslararası Hakemli
Biochimie, Erkisa M.,aydinlik seyma,Cevatemre Buse,AZTOPAL NAZLIHAN,AKAR REMZİ OKAN,ÇELİKLER KASIMOĞULLARI SERAP,YILMAZ VEYSEL TURAN,ARI FERDA,ULUKAYA ENGİN
The molecular targets of diclofenac differs from ibuprofen to induce apoptosis and epithelial mesenchymal transition due to alternation on oxidative stress management p53 independently in PC3 prostate cancer cells
2019 - Uluslararası Hakemli
Prostate International, ARISAN ELİF DAMLA,AKAR REMZİ OKAN,RENCÜZOĞULLARI ÖZGE,OBAKAN YERLİKAYA PINAR,ÇOKER GÜRKAN AJDA,AKIN BEYZA,DENER ELİF,KAYHAN ECEM,ÜNSAL ZEYNEP NARÇİN
A novel 1,4-naphthoquinone-derived compound induces apoptotic cell death in breast cancer cells
2019 - Uluslararası Hakemli
TURKISH JOURNAL OF BIOLOGY, KARAKAŞ DİDEM,AKAR REMZİ OKAN,GÖKMEN ZELİHA,DENİZ NAHİDE GÜLŞAH,ULUKAYA ENGİN
Key actors in cancer therapy: epigenetic modifiers
2019 - Uluslararası Hakemli
TURKISH JOURNAL OF BIOLOGY, AKAR REMZİ OKAN,Selvi Selin,ULUKAYA ENGİN,AZTOPAL NAZLIHAN
Effect of p53 on Diclofenac and Ibuprofen-induced ROS generation-dependent apoptosis on PC3 prostate cancer cells
Uluslararası
Fen Bilimleri ve Matematik Temel Alanı->Moleküler Biyoloji ve Genetik ,
Diclofenac increased ROS generation to proceed EMT processes p53 independently in PC3 cells
Ulusal
Fen Bilimleri ve Matematik Temel Alanı->Moleküler Biyoloji ve Genetik ,
A newly synthesized platinum complex as a potent antitumor drug candidate
Uluslararası
Fen Bilimleri ve Matematik Temel Alanı->Moleküler Biyoloji ve Genetik ,
MOKAD Genç Araştırmacı
2019 - Genç Bilim ve Sanat İnsanı Ödülü
İSTİNYE ÜNİVERSİTESİ/TIP FAKÜLTESİ/TEMEL TIP BİLİMLERİ BÖLÜMÜ/TIBBİ BİYOKİMYA ANABİLİM DALI/ - Diğer