She had her Bachelor’s degree from Biology department at Hacettepe University in 1991. She earned her Master’s degree from Ankara University Biotechnology Institute, Basic Biotechnology in 2005. She studied at Montpellier University Department of Medical Genetics- France as a researcher in 2005 and she received European Molecular Cytogenetics Diploma from Montpellier University. She earned her PhD degree from Ankara University Faculty of Medicine, Department of Medical Biology in 2011. She studied at Imperial Collage of London- England in Molecular Patology Laboratory Cancer Cytogenetics Unit as visiting researcher in 2013. She was assistant professor in Oncology Institute Department of Basic Oncology at Hacettepe University between 2015-2016. She has been assistant professor at Istinye University, Faculty of Medicine Department of Medical Biology since 2016. Her research areas are cancer cytogenetics, molecular cytogenetics and cancer epigenetics.
Araştırma Alanları
- Kanser Genetiği
- Lösemi Sitogenetiği ve Kanser Epigenetiği
Çalışma Alanları
- Sağlık Bilimleri Temel Alanı
- Tıbbi Biyoloji
- Phenotypic and functional characterization of subpopulation of Imatinib resistant chronic myeloid leukemia cell line, 2023
- Novel RUNX1 Variation in B-cell Acute Lymphoblastic Leukemia, 2023
- Downregulation of Stearoyl-CoA Desaturase 1 (SCD-1) Promotes Resistance to Imatinib in Chronic Myeloid Leukemia, 2023
- First report of t(1;9)(q21;q34) in Fanconi anemia as a preceeding chromosomal aberration before leukemia development, 2022
- First report of t(1;15)(q21;q11.2) and t(1;21)(q21;q11.2) anomalies in Burkitt Lymphoma, 2021
- Rare Cytogenetic Anomalies in Two Pediatric Patients with Acute Leukemia, 2020
- MDA-MB-231 Meme Kanseri Hücre Dizisinde Prostoglandin Endoperoksid H Sentaz 2 (PTGS2), Kalretikulin (CALR) ve Keratin-19 (KRT19) Genlerinin Transkripsiyon Aşamasında Anlatımlarının Araştırılması, 2020
- Expression Analysis in the Transcription Level of PTGS2, CALR, MAGE-A3 Genes in Non-Small Cell Lung Cancer, 2020
- Investigation of PTGS2, MAGE-A3, CALR, KRT19 and TMPRSS4 expressions in HCT116 colon cancer and PC3 prostate cancer cell lines, 2020
- Rare Cytogenetic Anomalies in Two Pediatric Patients with Acute Leukemia, 2020
- New mutations in KCNT2 gene causing early infantile epileptic encephalopathy type 57: Case study and literature review, 2020
- Aggressive Clinicopathological Course of Myeloma with t(3;16) (q21;q22) Cytogenetic Abnormality, 2019
- Çocukluk Çağı Lösemi Tanılı Hastalarda Sitogenetik Anomaliler, 2019
- Retrospective evaluation of chromosome 1 anomalies in hematologic malignancies: A single center study, 2019
- Hematological Neoplastic Disorders With Chromosome 3 Abnormalities, 2019
- Aggressive Clinicopathological Course of Myeloma with t(3;16) (q21;q22) Cytogenetic Abnormality, 2019
- Determining the frequency of iron overload at diagnosis in de novo acute myeloid leukemia patients with multilineage dysplasia or myelodysplasia-related changes: a case control study, 2019
- Cytogenetic anomalies in Multiple Myeloma patients:A single center study., 2019
- Characterization of imatinib-resistant K562 cell line displaying resistance mechanisms, 2018
- Characterization of imatinib-resistant K562 cell line displaying resistance mechanisms. Cell Mol Biol (Noisy-le-grand)., 2018
- Sole Infrequent Karyotypic Aberration Trisomy 6 in a Patient with Acute Myeloid Leukemia and Breast Cancer in Remission, 2017
- The Impact of Variant Philadelphia Chromosome Translocations on the Clinical Course of Chronic Myeloid Leukemia, 2016
- Comparison of Myelodysplastic Syndrome Prognostic Scoring Systems, 2016
- Clinical and pathological correlations of marrow PUMA and P53 expressions in myelodysplastic syndromes, 2015
- The roles of epigenetic modifications of proapoptotic BID and BIM genes in imatinib-resistant chronic myeloid leukemia cells, 2013
- Prognostic importance of additional cytogenetic anomalies in chronic myeloid leukemia, 2013
- P16 and p27 tumor suppressor gene methylation status in childhood Wilms tumor cases, 2011
- Secondary childhood acute myeloid leukemia with complex karyotypic anomalies including monosomy 7, monosomy 5 and translocation (110) after 131I-metaiodobenzylguanidine therapy for relapsed neuroblastoma, 2011
- Eksozomlar ve Kanserdeki Rolleri,
- Çoklu Organ Yetmezliğinde Oluşan Bağırsak Mikrobiyotasındaki Değişikliklerin Sağlıklı Türk Toplumunun Mikrobiyota Sonuçlarında Değerlendirilmesi,
- Microbiota in Cancer, 2020
- Diagnostic and Prognostic Importance of Leukemia Cytogenetics, 2019
- Monosomal karyotype in myelodisplastic syndrome and acute myeloid leukemia patients, 2019
- Determination of intestinal microbiota in pediatric patients who underwent allogenic stem cell transplantation before and after transplantation,
- Post remission treatment score for predicting the survival in acute myeloid leukemia: single centre experience., 2019
- Yeni bir sitogenetik anomaliye sahip Multipl myelom tanılı hastaya ait olgu sunumu,
- T(316)(q21q22) anomalisine sahip multipl myelom tanılı hastaya ait olgu sunumu,
- Çocukluk çağı akut lösemilerde görülen sitogenetik anomaliler,
- Imatinib Mesilat Dirençli ve Dirençsiz Kronik Myeloid Hücre Hatlarında Bim ve Bid Proapoptotik Genlerinin Polikomb Grup Proteinleri tarafından Epigenetik Regülasyonu, 2011
- Kronik Myeloid Lösemi KML Hastalarında ek Kromozomal Anomaliler ve Klinik Seyir ile İlişkileri,
- Yeni Tanı Multipl Miyelom da MM Konvansiyonel Sitogenetik Analiz KSA Verileri Anormal Karyotiplerin ve Kötü Prognoz Isareti Olan Bozuklukların Sıklıkları,
- Yeni Tanı Miyelodisplastik Sendrom MDS Hastalarında Konvansiyonel Sitogenetik Analiz Sonuçlar ve Dünya Sağlık Örgütü WHO Alt Tipleri ile Korelasyon,
- Oküler Lenfoma Tanısı Almıs Hasta Gruplarında p14 p16 p27 Tümör Süpresör Genlerinin Metilasyon Statülerinin Belirlenmesi, 2007
- Analysis of Genes in CML Etiology and Drug Resistance., 2018
- Investigation of the Taspine s antiproliferative antiangiogenic and apoptotic effects on U118 and U87 glioblastoma multiforme cell lines, 2014
- Epigenetic Regulation of bim and bid proapoptotik genes by polycomb group proteins in imatinib mesylate resistant and non resistant chronic leukemia cell lines, 2011
- Beta catenin does not interact with bim in K562 imatinib mesylate resistant CML cell line, 2010
- Determination of Methylation Statüs of p16 p27 Tumor Suppressor genes, 2008